Research for Commercial Purposes
We conduct research projects tailored to the specific needs of commercial clients, focusing on areas such as drug development, vaccine testing, and biomedical studies. Our team of experienced scientists and researchers collaborates closely with clients to design and execute studies that meet regulatory requirements and deliver actionable insights.
EXPLORATORY PHARMACOLOGY
Pain
a) Inflammatory Pain Model
Formalin-induced Pain (Acute)ortunities to innovate and grow
Capsaicin induced pain
Carrageenan-induced Hyperalgesia
Freund's Adjuvant-induced Hyperalgesia (Chronic)
MIA/MMT-induced OA
b) Neuropathic pain models
Chronic Constriction Injury
Sciatic Nerve Ligation
Spinal Nerve Ligation
Spared Nerve Injury
Diabetic neuropathy
c) Arthritis Pain Models
CFA induced arthritic pain
CAIA induced arthritis pain
d) Muscle Pain Models
Acid induced muscular pain
Sporadic shock induced muscle pain
Cold water induced pain
e) Visceral Pain
Acetic acid writhing model
Balloon inserted colon model
f) Post Operative Pain
Longitudinal incision on hind paw/calf induced pain
g) Mechanical & Thermal Nociception
Hot plate
Rat Pinch Model
Tail Flick
Visceral pain
Acetic Acid-induced Writhing
h) Other(s)
Fibromyalgia
Chronic Fatigue Syndrome
INFLAMMATION
a) Acute inflammation models
Carrageenan-induced paw edema
Croton oil/ Oxazolone-induced ear edema
Carrageenan-air pouch inflammation
Vascular permeability
UV-erythema in guinea pigs
Delayed Type Hypersensitivity
b) Chronic inflammation
Formaldehyde-induced arthritis
Collagen-induced Arthritis
Freund’s adjuvant-induced poly-arthritis
Sodium urate-induced gout
MIA/MMT-induced OA
c) Granuloma Pouch Technique
Croton pellet induced granuloma
Glass rod-induced granuloma
METABOLIC DISORDER MODELS
a) Diabetic Models
Alloxan-induced
STZ-induced
b) Obesity Models
Fructose-induced
HFD-induced
HEPATIC DISORDER
CCL4-induced hepatotoxicity
Acetaminophen- induced hepatotoxicity
MCD/CD diet-induced NASH model
GASTRIC DISEASES
NSAID-induced gastric ulcer
Pylorus ligation induced gastric ulcer
DSS induced colitis
Gastric Motility/gastric empting
NEUROPHARMACOLOGY
a) PARKINSONISM
MPTP induced Parkinsonism for Neuro-degeneration
b) LEARNING AND MEMORY
Elevated Plus Maze
Morris Water Maze
Contextual Fear Conditioning (CFC) test
Novel Object Recognition Test (NORT)
Novel Environment Recognition Test (NERT)
c) STRESS AND DEPRESSION
Forced Swim Test
Tail Suspension Test
Chronic Unpredictable Mild Stress
Chronic Fatigue Syndrome
Olfactory bulbectomy
d) ANXIETY
Stress-induced Hyperthermia
e) WOUND HEALING MODELS
Excision & Incision wound
Diabetes wound
Burn Wound
INFECTION MODELS
Thigh Infection in Mice
Lung Infection
Septicemia
Urinary Tract Infection
OTHER MODELS
Locomotor Activity test
Motor Liability test in rat with Rotarod
Customized protocols: tailored and designed to address different issues
REGULATORY TOXICOLOGY
GENERAL TOXICOLOGY
Abnormal Toxicity
Acute Toxicity
Repeated Dose Toxicity
- Sub-acute Toxicity
- Sub chronic Toxicity Study
- Chronic Toxicity studies
DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY
Fertility and Early Embryonic Development to Implantation Study in Rats (Segment I)
Pre-and Post-natal Development Study in Rats (Segment III)
Embryo-Fetal Development (Teratology) Studies in Rats and Rabbits
Developmental Screening Studies
One or Two Generation Studies
TOXICOKINETIC
Maximum Tolerable Dose (MTD)
Dose Range Finding (DRF)
Local Tolerance test
Neurotoxicity study
BIOCOMPATIBILITY TESTING
Implantation
Irritation
Sensitization
Pyrogenicity
Systemic toxicity
Cytotoxicity
Hemocompatibility
DMPK
PK-PD STUDIES
Single dose PK
Multiple-dose PK
Time Course of drug-concentration- Response Studies to Enable PK/PD Modeling
Dose Fractionation Studies to identify PK/PD Index of efficacy
PHARMACEUTICAL QC TESTING
Heparin Sodium: Identification, Abnormal Toxicity, Bioassay
Streptokinase: Identification, Abnormal Toxicity, Streptodornase activity, Streptolysin activity
Urokinase: Identification, Abnormal Toxicity, Bioassay, Thromboplastic contaminants
Enoxaparin: Anti-factor Xa activity, Anti-factor IIa activity
Hemolysis assays
COSMETICS TESTING
General Toxicity
Safety Testing
Skin Sensitization
Phototoxicity
Skin Penetration
